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This chapter discusses removal of contaminants from both ventilation and recirculated air used for conditioning building interiors. The filters mentioned in this chapter are primarily used for HVAC systems and for the protection of equipment. Complete air cleaning may require removing of airborne particles, microorganisms, and gaseous contaminants, but this chapter only covers removal of airborne particles and briefly discusses bioaerosols. Chapter 47 of the 2023 ASHRAE Handbook -- HVAC Applications covers the removal of gaseous contaminants. Chapter 62 of the 2023 ASHRAE Handbook -- HVAC Applications covers bioaerosols and UV air cleaners in more depth. Terminology Atmospheric Aerosols Aerosol Characteristics Air-Cleaning Applications Mechanisms of Particle Collection Types of Air Cleaners and Performance Air Cleaner Test Methods Selection and Maintenance Air Cleaner Installation Safety Considerations