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Exact Sciences’ Discovery Campus clinical laboratory building supports high-throughput molecular diagnostics testing, processing millions of human stool samples obtained via its colorectal cancer screening test annually. With such large volumes of odorous materials traveling throughout the facility, optimized operational capacity and IAQ were fundamental design requirements. Through extensive energy modeling and an emphasis on high-performance design, this 24-hour clinical processing and manufacturing facility incorporates an advanced HVAC ventilation and exhaust system.