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ISO 10159:2011 specifies the format of a manifest of web access reference pointers, information object identifiers, information object filenames and associated information required by a target IT system.

This enables local web access to the referenced information objects when a package containing the referencing document, the manifest and the objects (stored in files) is sent from a source clinical domain to a target clinical domain in which the server references are different from those in the source clinical domain.