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The Metropolitan Water District of Southern California is evaluating the hydrogen peroxide-ozone (PEROXONE) advanced oxidation process (followed by secondary disinfection with chloramines) for removal of taste and odor compounds, control of disinfection by-products (DBPs), and inactivation of microorganisms. This article reports the results of pilot-scale testing designed to optimize the H2O2:O3 ratio and to compare ozone and PEROXONE at different contact times. The tests described represent one phase of a five-phase PEROXONE pilot-scale study for treating water from the California State Water Project and from the Colorado River. Results to date indicate that the PEROXONE process requires a significantly lower applied ozone dosage to oxidize 2-methylisoborneol and geosmin as compared with ozone alone. The levels of DBPs formed when ozone or PEROXONE is used (followed by chloramines) are low, and PEROXONE (at H2O2:03 ratios of < 0.3) is comparable with ozone for the inactivation of microorganisms. Includes 26 references, tables, figures.