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The US Environmental Protection Agency established regulatory negotiations to refine the existing maximum contaminant level (MCL) for trihalomethanes (THMs) and to possibly introduce new MCLs for other disinfection byproducts (DBPs). The Information Collection Rule (ICR) was developed as part of the negotiations and requires water utilities to collect data on the occurrence and concentrations of DBPs and microorganisms. Membranes and granular activated carbon (GAC) treatment were determined to be the unit processes most likely to be effective for DBP precursor removal. This paper discusses the results of bench-scale experiments conducted to evaluate the ability of nanofiltration to remove DBP precursors under the requirements of the ICR.