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This paper presents portions of a testing program conducted to evaluate the application of ion-exchange (IX) technology for the removal of perchlorate from contaminated groundwater. The feasibility study consisted of two phases: laboratory bench-scale testing that focused on the screening of three IX resins and the evaluation of key process design parameters; and, pilot scale testing of three selected resins operated under fullscale conditions. All testing was conducted using groundwater collected from the San Gabriel Basin. The experimental conditions evaluated in each testing phase are discussed. Of the two types of strong-base anionic resins evaluated, hydrophobic polystyrene and hydrophilic polyacrylic, only the results from the polyacrylic resin testing are presented and discussed.