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This article discusses radionuclides in general, but it focuses on radium, uranium, and radon, which are the radionuclides of most concern to drinking water suppliers. Developed as the result of literature searches and interviews with personnel from the US Environmental Protection Agency and the California Department of Health Services, the article covers radionuclide chemistry, health effects, the occurrence of radionuclides, current and future regulations, treatment technologies, and monitoring. Includes 44 references, tables, figures.