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Chlorine dioxide and its organic reaction products may present a higher risk from acute toxicity than chlorine, combined chlorine, or ozone, but its use may be advantageous when the generation of possibly carcinogenic byproducts by other disinfectants is considered. However, the generation of carcinogenic byproducts might be reduced by removal of precursor organic material from source water, in which case the question of disinfection byproducts would assume less importance. A variety of treatment options are available, and the most immediate problem is to develop data on which informed choices can be based. Includes 19 references, tables.