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This article discusses how early indications from the US Environmental Protection Agency (USEPA) indicate that robust new occurrence data collected by water suppliers under the Unregulated Contaminant Monitoring Rule (UCMR) will likely justify not regulating at least five targeted chemicals. As USEPA officials explained during the meeting, their approach for evaluating which, if any, Contaminate Candidate List (CCL2) contaminants ultimately qualify for a final regulatory determination requires the agency to establish a potential health reference level (HRL) and a known or likely level and frequency of occurrence for each, noting that the law requires no fewer than five to be considered in each RD cycle. USEPA's health and occurrence findings on the 14 contaminants it is evaluating as potential regulatory determination (RD2) candidates are briefly summarized in this article. The 14 contaminants include: 1,1,2,2-Tetrachloroethane; 1,3-Dichloropropene; 2,4- and 2,6-Dinitrotoluene (DNT); Boron; DCPA degradates; DDE; DPTC; Fonofos; Metolachlor; MTBE; Perchlorate; and, Terbacil. Includes tables.