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Biological activity on granular activated carbon (GAC) may significantly enhance the treatment process. Shifting the pathway for contaminant removal from adsorption to biodegradation reduces biodegradable organics and increases sorptive capacity for non-degradable or slowly degradable compounds. Biodegradation and adsorption of natural organic matter (NOM) were studied in a laboratory-scale GAC reactor. Ozonation was found to encourage biofilm growth and biodegradation of NOM. Biofilm organisms grown on ozonated NOM readily degraded trace concentrations of phenol. Includes 23 references, table, figures.