-
-
Available Formats
- Options
- Availability
- Priced From ( in USD )
-
Available Formats
-
- Secure PDF 🔒
- Immediate download
- $190.50
- Add to Cart
-
- Printed Edition
- Ships in 1-2 business days
- $190.50
- Add to Cart
-
- Printed Edition + PDF
- Immediate download
- $257.81
- Add to Cart
Customers Who Bought This Also Bought
-
ISO 22174:2005
Priced From $81.00 -
ISO 15189:2022
Priced From $250.00 -
BS EN ISO 15189:2022+A11:2023
Priced From $398.78 -
ISO Guide 30:2015
Priced From $81.00
About This Item
Full Description
Blood ccfDNA profiles can change significantly after blood collection from the donor (e.g. release of genomic DNA from white blood cells, ccfDNA fragmentation and ccfDNA quantity change). Special measures need to be taken to secure good quality blood samples for ccfDNA analysis and storage.
Different dedicated measures need to be taken for preserving blood genomic DNA. These are not described in this Technical Specification. Blood genomic DNA is covered in CEN/TS 16835-2, Molecular in vitro diagnostic examinations - Specifications for pre-examination processes for venous whole blood - Part 2: Isolated genomic DNA
NOTE CcfDNA obtained from blood by the procedures suggested in this document can contain DNA present in exosomes [3] [4].
DNA from pathogens present in blood is not covered by this Technical Specification.
Cross References:
EN ISO 15189:2012
ISO 15189:2012
ISO 15190
EN ISO 22174:2005
ISO 22174:2005
ISO Guide 30:2015
SRM 2372
All current amendments available at time of purchase are included with the purchase of this document.
Document History
-
BS EN ISO 20186-3:2019
Molecular in-vitro diagnostic examinations. Specifications for pre-examination processes for venous whole blood-Isolated circulating cell free DNA from plasma- Most Recent
-
BS PD CEN/TS 16835-3:2015
viewing
Molecular in vitro diagnostic examinations. Specifications for pre-examination processes for venous whole blood-Isolated circulating cell free DNA from plasma- Historical Version