When evaluating indoor environments for human health and comfort, six thermo-physical factors are normally considered: dry bulb temperature, humidity, mean radiant temperature, air velocity, metabolic activity level, and thermal properties of clothing. Additionally, air quality factors such as gaseous and particulate concentrations should be considered. Air movement and humidity affect both the thermal and "non-thermal" responses of man to the environment, and therefore must be considered among the most important physical factors. This paper addresses the physiological and affective responses of humans to these two factors.