CGA G-16 is intended for the suppliers, distributors, and users of arsine and its handling equipment. The publication includes guidance for design of equipment, selection of cylinders and valves, and handling controls and safety practices. Guidelines on the operational steps associated with the use of arsine and arsine mixtures as well as fire protection, gas detection, ventilation, and related safeguards are also included. The manufacture, purification, and analysis of arsine is beyond the scope of this publication, although the general guidance given is also relevant to these processes.

This publication was written to address the high toxicity and flammability of arsine where the consequences of improperly handling arsine could cause injury, death, and/or facility damage. This publication provides an understanding of the potential hazards involved in handling arsine and the guidelines to take to minimize risk potential.