This document provides guidance on various ways organizations can implement the requirements of ANSI Z10. This guidance contains no requirements, and its implementation is completely voluntary. Organizations are free to approach the implementation of the Z10 standard’s requirements in any way that fits their culture, objectives, and relationships with their workers, contractors, and interested parties. The Z10 Standards Development Committee offers this guidance to help organizations maximize the benefits of their occupational health and safety management system (OHSMS) in continually improving their occupational health and safety (OHS) performance (see Figure 1). The guidance contains requirement-by-requirement suggestions on implementing and maintaining an OHSMS, as well as detailed descriptions of state-of-the-art, cutting-edge approaches to improving OHS performance.