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This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of mainstream cigarette smoke by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

 

Document History

  1. DANSK DSF/ISO/FDIS 19290


    Cigarettes – Determination of tobacco specific nitrosamines in mainstream cigarette smoke – Method using LC-MS/MS

    • Historical Version
  2. DANSK DS/ISO 19290

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    Cigarettes – Determination of tobacco specific nitrosamines in mainstream cigarette smoke – Method using LC-MS/MS

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  3. DANSK DS/ISO 19290


    Cigarettes – Determination of tobacco specific nitrosamines in mainstream cigarette smoke – Method using LC-MS/MS

    • Historical Version