BS ISO 20391-1:2018 defines terms related to cell counting for biotechnology. It describes counting of cells in suspension (generally cell concentration) and cells adhered to a substrate (generally area density of cells). It provides key considerations for general counting methods (including total and differential counting, and direct and indirect counting) as well as for method selection, measurement process, and data analysis and reporting.

This document is applicable to the counting of all cell types ? mammalian and non-mammalian (e.g. bacteria, yeast) cells.

This document is not intended for counting of cells while in a tissue section or a biomaterial matrix.

Several sector/application-specific international and national standards for cell counting currently exist. When applicable, the user can consult existing standards when operating within their scope (specific measurement techniques and/or applications).


Cross References:
DIN 58932-5
ASTM F 2739-08
DIN 58932-2
ISO Guide 33
ISO Guide 98-3
ISO 5725-2:1994
DIN 58932-3
DIN 58932-4
ASTM D4455-85 (2014)
ISO 20391-2
ASTM F 2149-01
DIN 58932-1
ASTM F2944-12
ISO 11843-1:1997
ISO/IEC Guide 99:2007
ISO 5725-1:1994
ISO 13528:2015
ISO 5725-3:1994
ISO 17511:2003 Ed 1
ISO 5725-6:1994
ISO 10718:2002 Ed 2
ISO 8196-3:2009 Ed 1
ISO 13366-1:2008 Ed 2


All current amendments available at time of purchase are included with the purchase of this document.